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                      碩士生陳佳佳的論文在JOURNAL OF COLLOID AND INTERFACE SCIENCE 刊出
                      發布時間:2018-05-29 09:13:18     發布者:yz     瀏覽次數:

                      標題: Enhanced physical and biological properties of silk fibroin nanofibers by layer-by-layer deposition of chitosan and rectorite

                      作者: Chen, JJ (Chen, Jiajia); Cheng, G (Cheng, Gu); Liu, R (Liu, Rong); Zheng, Y (Zheng, Yue); Huang, MT (Huang, Mengtian); Yi, Y (Yi, Yang); Shi, XW (Shi, Xiaowen); Du, YM (Du, Yumin); Deng, HB (Deng, Hongbing)

                      來源出版物:JOURNAL OF COLLOID AND INTERFACE SCIENCE卷:523頁碼: 208-216 DOI:10.1016/j.jcis.2018.03.093 出版年: AUG 1 2018

                      摘要:The search for biodegradable and biocompatible materials applied to the antibacterial field has become a significant topic of interest worldwide. In this study, the electrospinning and electrostatic layer-by-layer self-assembly (LBL) techniques were applied to achieve composite mats with enhanced physical and biological properties. Electrospun silk fibroin (SF) was selected as the substrate, and chitosan (CS) and rectonte (REC) were assembled on the surface of the substrate as positively and negatively charged layers via electrostatic LBL. The morphology, composition and structure of the mats were examined, and the results suggested that LBL modification was successful. In addition, the variation of the bilayer numbers and the component of the outmost layer could affect the morphology and the physical and biological properties of LBL mats. Additionally, the morphology and the water contact angle investigation results of the as-prepared mats indicated that the surface features were changed through the LBL process, resulting in a rougher surface than in pure SF mats. Moreover, the mechanical properties of the SF mats were improved after the LBL process. Furthermore, the antibacterial activity of the LBL self-assembled SF mats against E. coll and S aureus with a concentration of 10(6) CFU/mL were 84 and 92%, respectively. The cellculture experiments demonstrated that the mats maintained superior biocompatibihty after the introduction of CS and REC.

                      入藏號: WOS:000431745500022

                      文獻類型:Article

                      語種:English

                      作者關鍵詞:Silk fibroin; Chitosan; Rectorite; Layer-by-layer; Antibacterial properties; Biocompatibility

                      擴展關鍵詞: ENDOTHELIAL-CELL ADHESIVENESS; ANTIBACTERIAL ACTIVITY; GOLD NANOPARTICLES; BONE REGENERATION; EDIBLE FILMS; SILVER; MATS; MEMBRANES; SURFACES; COATINGS

                      通訊作者地址:Deng, HB (reprint author), Wuhan Univ, Sch Resource & Environm Sci, Hubei Key Lab Biomass Resource Chem & Environm Bi, Hubei Int Sci & Technol Cooperat Base Sustainable, Wuhan 430079, Hubei, Peoples R China.

                      電子郵件地址:hbdeng@whu.edu.cn

                      地址:

                      [Chen, Jiajia; Liu, Rong; Huang, Mengtian; Yi, Yang; Shi, Xiaowen; Du, Yumin; Deng, Hongbing] Wuhan Univ, Sch Resource & Environm Sci, Hubei Key Lab Biomass Resource Chem & Environm Bi, Hubei Int Sci & Technol Cooperat Base Sustainable, Wuhan 430079, Hubei, Peoples R China.

                      [Cheng, Gu; Zheng, Yue] Wuhan Univ, Sch & Hosp Stomatol, State Key Lab Breeding Base Basic Sci Stomatol Hu, Wuhan 430079, Hubei, Peoples R China.

                      [Cheng, Gu; Zheng, Yue] Wuhan Univ, Sch & Hosp Stomatol, Minist Educ, Key Lab Oral Biomed, Wuhan 430079, Hubei, Peoples R China.

                      [Huang, Mengtian] Guangxi Univ, Sch Chem & Chem Engn, Guangxi Key Lab Petrochem Resource Proc & Proc In, Nanning 530004, Peoples R China.

                      影響因子:4.233

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